Hello Friends ! , I want to talk to you about CPR, which stands for Cardio pulmonary Resuscitation. We use CPR when someone has collapsed and is not breathing, because it can keep people alive until emergency services arrive. Learning these simple life-saving skills is as easy as ABC – all you have to remember is the “Doctor’s ABC”.
Doctor’s ABC :-
D is for Danger:
First, look around carefully to make sure the area is safe for yourself and others before approaching.
R is for Response:
Shake them gently by the shoulders and ask them loudly “Are you alright?” If there is no response, you need to…
S is for :
Shout for help, as any assistance will be helpful.
A is for Airway:
Gently tilt the head back like this, to open up the airway.
B is for Breathing:
Look, Listen and Feel for signs of normal breathing: LOOK for normal chest movements, LISTEN for normal breathing sounds and try to FEEL their breath against your face. Do this for no more than 10 seconds. If there is no sign of breathing, or if they are breathing in an unusual, noisy way, we need to start CPR. First, make sure that an ambulance is on its way. If you have someone else with you, ask them to make the call. Putting the phone on speaker mode is useful as the ambulance service can talk you through the steps.
C is for Circulation:
Circulation means the flow of blood around the body, and when the heart stops pumping, we need to take over this role by pushing down hard and fast on the chest. Start by placing the heel of one hand at the centre of the person’s chest and interlock your fingers like this. With arms straightened, press down hard and fast, letting the chest come back up fully each time. Fast means around 2 times every second (metronomesound) and hard means that the chest needs to go down by about 5 centimetres. This might sound a lot but you do need to push hard for it to be effective. If you have been trained, you can give 2 ‘rescuebreaths’ after every 30 compressions, as this helps provide some oxygen. However, if you have not been trained or are not comfortable, just keep going with ‘Hands-only’ continuous chest compressions. If someone else is with you, swap over if you begin to feel tired, and don’t stop until either a health professional takes over,or the person is definitely breathing normally.
Sometimes, we can add another step – ‘D’. D is for Defibrillation, which is about delivering a shock to restart the heartbeat. Some public areas and workplaces have an easy-to-use defibrillator on site, called an Automatic External Defibrillator, or AED. Automatic means that it is the machine that decides what to do, so you can’t go wrong, and it even talks you through the steps. If there is no AED available, keep going with CPR until the ambulance arrives. That’s it! So to recap: remember DR’S ABC and if you have it, D. That’s D for Danger, R for response. S for shout for help, A for Airway, B for Breathing, C for Circulation and D for Defibrillation. In this Health Sketch, we’ve explain you the simple steps you can take to help someone who has collapsed, is not breathing, or not breathing normally. Why not take a training course to practice these steps. Share this knowledge with friends and family to make sure we all know what to do.
Hii Friends…One of the most mind-boggling facts is Today I am going to give you information about best places to inject insulin into the body and how to do it. Please read before injecting your insulin.Your healthcare provider may recommend that you inject insulin using a syringe to help you control your blood sugar level. Injecting insulin with a syringe involves choosing an injection site, preparing the syringe and insulin, and then injecting the insulin into your body. Your healthcare professional will tell you what type of insulin you need as well as when and how much you need to inject. You would require alcohol wipes, your jug of insulin, another syringe for each infusion, and a sharps removal compartment to discard the pre-owned syringes.”
A disposable syringe has the following parts: A barrel, a plunger,a needle cap, and a needle. Selecting the Injection Site Before injecting your insulin, select the injection site on your body. The areas for insulin injection include the abdomen or belly, upper arms, the thighs, and the buttocks.When selecting the injection site, be sure you use a different spot each time you give yourself an injection. Leave at least one inch away from the last injection spot, inject your insulin at least two inches from your belly button, and choose a spot at least one inch or farther from any scar or mole.
Preparing the Syringe and Insulin :-
Wash your hands with soap and water and then dry them.
If your insulin needs to be mixed, gently roll the bottle between your hands. Do not shake the bottle because it may cause bubbles to form in your insulin. Before injecting yourself, check the insulin in the bottle to make sure it is the type of insulin your doctor prescribed for you, not past the expiration date, and the insulin is free of clumps.
Remove the cap from your insulin bottle. Use an alcohol wipe to clean the rubber stop peron the top of the bottle.
Remove the syringe from its package. “Make bound to utilize another syringe whenever you infuse insulin.”
Remove the needle cap from the syringe. Do not touch the needle or allow it to touch any surface, and do not use the syringe if the needle is bent. Some syringes have a cap over the plunger that you may need to remove as well.
Pull back the plunger to draw in an amount of air that is equal to your insulin dose.
Hold your insulin bottle securely on a flat surface.Push the needle through the rubber on the top of the bottle. Push the plunger to inject the air into the insulin bottle. Leave the needle in the bottle. This helps to keep the right amount of pressure in the bottle and makes it easier to draw insulin into the syringe.
With the needle still within the bottle, turn the bottle and syringe the wrong way up .
Pull back the plunger to fill the syringe will just a touch quite the insulin dose you need. If you see air bubbles, tap the barrel of the syringe with your finger to make them rise to the top. Slowly, push in the plunger just enough to push out the air and extra insulin.
Carefully check to make sure the amount of insulin in the syringe matches your insulin dose. Pull the needle out of the bottle and carefully lay the syringe on a flat, clean surface. Make sure the needle does not touch anything.
Injecting the Insulin :-
Clean your injection site with an alcohol wipe. Use a circular motion to wash a spot about two inches wide.
Pinch a two-inch fold of skin in the clean injection site.
Hold the syringe like a pencil and quickly insert the needle straight into your skin at a 90-degree angle. Make sure the whole needle enters your skin.
Push the plunger all the way down to inject the insulin into the fat tissue beneath your skin. Slowly, count to 5 before removing the needle to form sure you’ve got injected all of the insulin.
Pull the needle straight out to remove it.
Throw away the syringe into your sharps disposal container. Never throw your syringes or needles directly into the trash. Contact your healthcare provider if you have questions about injecting your insulin or if your blood sugar level stays above or below your target range.
What’s up guys ! Swapnil Patil here and today I’m going to talk about the Action block on Instagram. So first of all what is an action block and why do they exist an Instagram action block is when you can’t complete an action with your account. For example, you’ll try and comment on a post and you’ll get a notification at popping up to tell you to slow down or you’ve been doing too many actions so it won’t let you take it any further and it’s really frustrating it stops you from being able to use Instagram pretty much you can’t put captions you can’t comment on post you can’t like posts you can’t follow people and it’s a big problem action block is a big problem. And now although the action block is trying to keep Instagram safe from spam bots and all that. Sometimes it can be very annoying when your account gets action blocked and you don’t even deserve to be action blocked.
I’m going to give you eight different ways that you can remove the action block as soon as possible and now some of these methods I have done myself and some of these methods I have found by doing research online and watching other people’s videos and online blogs and forums.
1) Edit Bio :-
First tip is to edit your Instagram bio, people say that if you edit your Instagram bio it makes you look a lot less like a bot so Instagram is more likely to remove the action block .
2) Install / Reinstall:-
Tip number two is just to uninstall and reinstall Instagram on your phone now this one I don’t think it would work in my opinion but people have said that it’s worked on other forums. The reason why I don’t think it’ll work is when you uninstall it Instagram saves your cookies and data on that phone any way so when you reinstall it, it will still have the kind of information. And I’m pretty sure an action block is linked with an account so that won’t necessarily work but try anyway .
3) Request form action blocked message :-
Tip number three is to send a request when the actual block message pops up now sometimes on the message you get the option to send a request saying they’ve made a mistake, sometimes it says tell us if you think we’ve made a mistake and then you just send a request saying that they have some times that has worked for people and if that doesn’t happen this is .
4) Report a Problem :-
Tip number four you just need to go into your settings, go into help, tap on are report a problem and then select something isn’t working and just say that you’ve been action blocked and you shouldn’t have been this has fix the problem for me before I’ve reported this a couple of times and then like a few hours later or the next day I don’t seem to have been action blocked anymore.
5) Use another device switch device data :-
Tip number five is to use another device and switch to data on that device the reason being is because action blocks are often linked to IP addresses so you could have action blocks across your entire phone meaning that all the Instagram accounts you use on your phone are going to be action blocked and the reason you have to switch to data is because if you switch to data you won’t use the same IP as your Wi-Fi address now a lot of the times this has been one of the best methods for me but I have had it occasionally where an action block has been linked to my account and is gone from one account from one device to another device but hopefully this should be one of the best solutions for you.
6) Delete third-party apps :-
Tip number six is to delete third-party apps and stop all BOTS now a lot of the time people have an ongoing action block because they’re running like Jarvee or Follow liker at the same time and it’s just causing them to constantly get action blocked this is because their bot software doesn’t look authentic at all and Instagram can tell it’s a bot software or they’re just doing way too many actions Instagram is constantly going to be blocking that account so I highly suggest if you are getting action block that you definitely slow down on the automation and remove third-party apps from your Instagram account .
7) Link your Instagram account to a Facebook page :-
Tip number seven is to link your Instagram account to a Facebook page now I’ve never done this myself but it kind of makes sense Instagram normally has the action Block in place to stop Instagram BOTS and spam accounts just taking over the platform so if you link it to a Facebook page it’s just going to look more real and authentic so Instagram is more likely to unblock your account and I’ve never tried this one myself but again people have said that it’s worked for them .
8) Wait :-
Tip number eight is probably the best one and the easiest one although you have to be patience it’s just to wait it out most of the time my action block slast a minimum of eight hours and a maximum of 24 I know sometimes they can be like weeks which is ridiculous there’s not much you can do to be honest if none of the previous tips worked for you so yeah you just got to wait it out and make sure that you avoid doing something that will cause you to get action blocked in the future and I know the most frustrating thing is that a lot of the time people get action blocked for literally doing nothing like I’ve had an Instagram account where I have maybe gone on it once every two days and I go on it once to follow one person and I just get action block then it is really annoying it doesn’t make sense. but now I’ve given you my tips I’m just going to give you a couple of tips to avoid getting blocked in the future so like I said if you’re using Instagram BOTS and software if you get an action block it is normal don’t be surprised most of the time they don’t last more than 12 hours but you can’t expect to have Java on full-blast and not get an action block if you’re using it at the same time and then my second tip is that if you’re not using any software just try and make sure you’re not abusing the follow button that you’re not trying to follow 200 people within an hour throughout the entire day because obviously you’re gonna action block them and then my third tip is probably try and not run more than five accounts from the same IP address try and switch IP addresses I like to keep it three accounts to my IP address but action blocks can be to the entire IP so if it’s seeing loads of different Instagram accounts running different actions from the same IP it’s most likely that a few of these accounts are getting action blocked.
Hii Friends… Today I am going to give you information about Biomolecules in cell.Biology and its subfields of biochemistry and molecular biology study biomolecules and their reactions. Most biomolecules are organic compounds, and just four elements—oxygen, carbon, hydrogen, and nitrogen—make up 96% of the human body’s mass. But many other elements, such as the various biomolecules, are present in small amounts.Let me explain some information about Biomolecules.
Biomolecules in the cell
A. Carbohydrates : The word carbohydrates ‘hydrates of carbon’. They are also called saccharides. They are biomolecules made from just three elements: carbon, hydrogen and oxygen with the general formula (CH,O),. They contain hydrogen and oxygen in the same ratio as in water (2:1). Carbohydrates can be broken down (oxidized) to release energy. The means Based on number of sugar units, carbohydrates are classified into three types namely, monosaccharides, disaccharides and polysaccharides.
1. Monosaccharides: These are the simplest sugars having crystalline structure, sweet taste and soluble in water. They cannot be further hydrolysed into smaller molecules. They are the building blocks or monomers of complex carbohydrates. They have the general molecular formula (CH,O), where n can be 3, 4, 5, 6 and 7. They can be classified as triose, tetrose, pentose, etc. Monosaccharides containing the aldehyde (-CHO) group are classified as aldoses e.g. glucose, xylose, and those with a ketone (-C=O) group are classified as ketoses. eg .ribulose, fructose.
Structure of Glucose :-
a. Glucose : It is the most important fuel in living cells. Its concentration in the human blood is about 90mg per 100ml of blood. The small size and solubility in water of glucose molecules allows them to pass through the cell membrane into the cell. Energy is released when the molecules are metabolised by cellular respiration.
b. Galactose : It looks very similar to glucose molecules. They can also exist in a and B forms. Galactose react with glucose to form the dissacharide lactose. However, glucose and galactose cannot be easily converted into one another. Galactose cannot play the same role in respiration as glucose.
c. Fructose : It is the fruit sugar and chemically it is ketohexose but it has a five-atom ring rather than a six-atom ring. Fructose reacts with glucose to form the sucrose, a disaccharide.
2. Disaccharides : Monosaccharides are rare in nature.Most sugars found in nature are disaccharides. Disaccharides is formed when two monosaccharides react by condensation reaction releasing a water molecule. This process requires enegy. A glycosidic bond forms and holds the two monosaccharide units together. Sucrose, lactose and maltose are examples of disaccharides. Sucrose is a non- reducing sugar since it lacks free aldehyde or ketone group. Lactose and maltose are reducing sugars. Lactose also exists in beta form, which is made from B-galactose and B-glucose. Disaccharides are soluble in water, but they are too big to pass through the cell membrane by diffusion. They are broken down in the small intestine during digestion. Thus formed monosaccharides then pass into the blood and through cell membranes into the cells.
Structure of Maltose :-
Monosaccharides are used very quickly by cells but if a cell is not in need of all the energy released immediately then it may get stored. Monosaccharides are converted into disaccharides in the cell by condensation reactions, which result in the formation of polysaccharides as macromolecules. These are too big to escape from the cell.
Polysaccharides : Monosaccharidescan undergo a series of condensation reactions, adding one unit after the other to the chain till a very large molecule (polysaccharide) is formed. This is called polymerization. Polysaccharides down by hydrolysis are broken into monosaccharides. The properties of a polysaccharide molecule depend on its length, branching, folding and coiling.
a. Starch : Starch is a stored food in the plants. It exists in two forms: amylose and amylopectin. Both are made from a-glucose. Amylose is an unbranched polymer of a-glucose. The molecules coil into a helical structure. It forms a colloidal suspension in hot water. Amylopectin is a branched polymer of a-glucose. It is completely insoluble in water.
b. Glycogen : It is amylopectin with very short distances between the branching side-chains. Glycogen is stored in animal body particularly in liver and muscles from where it is hydrolysed as per need to produce glucose.
c. Cellulose : It is a polymer made from B-glucose molecules and the polymer molecules are ‘straight’. Cellulose serves to form the cell walls in plant cells. These are much tougher than cell membranes. This toughness is due to the arrangement of glucose units in the polymer chain and the hydrogen-bonding between neighbouring chains.
Biological significance of Carbohydrates: It supplies energy for metabolism. Glucose is the main substrate for ATP synthesis. Lactose, a disaccharide is present in milk provides energy to lactating babies. Polysaccharide serves as structural component of cell membrane, cell wall and reserved food as starch and glycogen. __________________________________________________
These are group of substances with greasy consistency with long hydrocarbon chain containing carbon, hydrogen and oxygen. In lipids, hydrogen to oxygen ratio is greater than 2:1 (in carbohydrates it is always 2:1). Lipid is a broader term used for fatty acids and their derivatives. They are soluble in organic solvents (non-polar solvents). Let’s understand what fatty acids are. Fatty acids are organic acids which are composed of hydrocarbon chain ending in carboxyl group (-COOH). They can be saturated fatty acids with no double bonds between the carbon atoms of the hydrocarbon chain. Palmitic and stearic acids found in all animal and plant fats are examples of saturated fatty acids.
Unsaturated fatty acids are with one or more double bonds between the carbon atoms of the hydrocarbon chain. Oleic acid found in nearly all fats and linoleic acid found in many seed oils are examples of unsaturated fatty acids. These fatty acids are basic molecules which form different kinds of lipids. Lipids may be classified as simple, compound and derived lipids.
Simple Lipids : These are esters of fatty acids with various alcohols. Fats and waxes are simple lipids. Fats are esters of fatty acids with glycerol (CH,OH-CHOH-CH,OH). Triglycerides are three molecules of fatty acids and one molecule of glycerol. Generally, unsaturated fats are liquid at room temperature and are called oils. Unsaturated fatty acids are hydrogenated to produce fats e.g. Vanaspati ghee. Fats are a nutritional source with high calorific value. Fats act as reserved food materials. In plants it is stored in seeds to nourish embryo during germination. In animals fat is stored in the adipocytes of the adipose tissue. Fats deposited in subcutaneous tissue act as an insulator and minimise loss of body heat. Fats deposited around the internal organs act as cushions to absorb mechanical shocks. Wax is another example of simple lipid. They are esters of long chain fatty acids with long chain alcohols. They are most abundant in the blood, the gonads and the sebaceous glands of the skin. Waxes are not as readily hydrolysed as fats. They are solid at ordinary temperature. Waxes from water insoluble coating on hair and skin in animals , waxes from an outer coating on stems , leaves and fruits.
Compound lipids : These are ester of fatty acids containing other groups like phosphate (Phospholipids), sugar (glycolipids), etc. They contain a molecule of glycerol, two molecules of fatty acids and a phosphate group or simple sugar. Some phospholipids such as lecithin also have a nitrogenous compound attached to the phosphate group. Phospholipids have both hydrophilic polar groups (phosphate and nitrogenous group) and hydrophobic non-polar groups (hydrocarbon chains of fatty acids). Phospholipids contribute in the formation of cell membrane. Glycolipids contain glycerol, fatty acids, simple sugars such as galactose and nitrogenous base. They are also called cerebrosides. Large amounts of them have been found in the brain white matter and myelin sheath.
Derived lipids : They are composed of fused hydrocarbon rings (steroid nucleus) and a long hydrocarbon side chain. One of the most common sterol is cholesterol. It is widely distributed in all cells of the animal body, but particularly in nervous tissue. Cholesterol exists either free or as cholesterol ester. Adrenocorticoids, sex hormones (progesterone, testosterone) and vitamin D are synthesised from cholesterol. Cholesterol is not found in plants. In plants, sterols exist chiefly as Phytosterols. Yam Plant (Dioscorea) produces a steroid compound called diosgenin. It is used in the manufacture of antifertility pills. i.e. birth control pills. __________________________________________________
C .Proteins :
Protein is a macronutrient that is essential to building muscle mass. It is commonly found in animal products, though is also present in other sources, such as nuts and legumes.
Classification of Proteins: On the basis of structure , Proteins are classified into three categories :
Simple proteins: Simple proteins on hydrolysis yield only amino acids. These are soluble one or more solvents. Simple proteins may be soluble in water. Histones of nuclcoproteins histones are not coagulated by heat. Albumins are also soluble in water but they get coagulated are soluble in water. Globular molecules of on heating. Albumins are widely distributed c.g. egg albumin, serum albumin and legumelin of pulses are albumins.
Conjugated proteins : Conjugated proteins consist of a simple protein united with some non-protein substance. The non-protein group is called prosthetic group c.g. haemoglobin. Globin is the protein and the iron containing pigment haem is the prosthetic group. Similarly, nucleoproteins have nucleic acids as prosthetic group. On this basis, proteins are classified as glycoproteins and mucoproteins. Mucoproteins are carbohydrate-protein complexes e.g. mucin of saliva and heparin of blood. Lipopoteins are lipid-protein complexes e.g. conjugate protein found in brain, plasma membrane, milk etc.
Derived Proteins : These proteins are not found in nature as such. These proteins are derived from native protein molecules on hydrolysis. Metaproteins, peptones are derived proteins. Derived proteins.
D. Nucleic Acids :
Swiss biochemist, Friederich Miescher (1869) discovered and isolated nucleic acids from the pus cells. By 1938, it became evident that nucleic acids are of two types- deoxyribose nucleic acid (DNA) and ribose nucleic acid (RNA). DNA is found in chloroplasts and mitochondria. DNA is the hereditary material in most of the organisms. The nucleic acids are among the largest of all molecules found in living beings. They contain three types of molecules a) 5 carbon sugar, b) Phosphoric acid and c) Nitrogen containing bases. Three join together to form a nucleotide of nucleic acid.
1.Structure of DNA : DNA has a double-helix structure.The sugar and phosphate lie on the outside of the helix, forming the backbone of the DNA. The nitrogenous bases are stacked in the interior, like the steps of a staircase, in pairs; the pairs are bound to each other by hydrogen bonds. Every base pair in the double helix is separated from the next base pair by 0.34 nm. The two strands of the helix run in opposite directions, meaning that the 5′ carbon end of one strand will face the 3′ carbon end of its matching strand. Only certain types of base pairing are allowed. For example, a certain purine can only pair with a certain pyrimidine. This means A can pair with T, and G can pair with C. This is known as the base complementary rule. In other words, the DNA strands are complementary to each other. If the sequence of one strand is AATTGGCC, the complementary strand would have the sequence TTAACCGG. During DNA replication, each strand is copied, resulting in a daughter DNA double helix containing one parental DNA strand and a newly synthesized strand.
2. Structure of Ribonucleic Acid (RNA): Another nucleic acid found in the living organisms is Ribose nucleic acid. In most of the organisms it is not found to be hereditary material but in certain organisms like tobacco mosaic virus, it is the hereditary material. Like DNA, ribose nucleic acid also consists of polynucleotide chain with the difference that it consists of single strand. In some cases e.g. Reovirus and wound tumour virus, RNA is double stranded. The nucleotides of RNA have ribose sugar instead of the deoxyribose sugar as in the case of DNA. Three types of cellular RNAs have been distinguished : (a) messenger RNA (b) ribosomal RNA (c) transfer RNA mRNA carries genetic information for arranging amino acids in definite sequence. It is linear polynucleotide. It accounts 3% of cellular RNA. Its molecular weight is several million. mRNA molecule carrying information to form a complete polypeptide chain is called cistron. Size of mRNA is related to the size of message it contains. Synthesis of mRNA begins at 5′ end of DNA strand and terminates at 3′ end. rRNA form 50-60% part of ribosomes. It accounts 80-90% of the cellular RNA.It is synthesized in nucleus. Kurland (1960) discovered it. It gets coiled here and there due to intrachain complementary base pairing. tRNAmolecules are much smaller consisting of 70-80 nucleotides. It is also single stranded but to number of complementary base sequences after pairing, it is shaped like clover-leaf (Holley, 1965). Each tRNA can pick up particular amino acid. Following four parts can be recognized on tRNA 1) DHU arm (Dihydroxyuracil loop / amino acid recognition site 2) Amino acid binding site 3) Anticodon loop / codon recognition site site. 4) Ribosome recognition In the anticodon loop of tRNA, three unpaired nucleotides are present called as anticodon which pair with codon present on mRNA. The specific amino acids is attached at the 3′ end in acceptor stem of clover leaf of tRNA.